Animals with human genes and cells
November 9, 2009 11:59pmBritain’s Academy of Medical Sciences has launched an imaginative new study - on the use in research of animals containing human genes or cells.
“This area of science has had very little public discussion, though it has been scientifically very important and has led to some important medical advances,” says Martin Bobrow, the Cambridge University medical geneticist who will lead the study.
Animals containing human material - mostly transgenic mice with genes of human origin - are used routinely in laboratories world-wide. They have enabled researchers to make groundbreaking advances in understanding the causes and devising treatments of disease.
However, increasingly powerful methods for introducing human material into animals, including new stem cell technologies and ways to transfer many genes together, will present new opportunities and significant regulatory and ethical challenges in the future.
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